Chronic pain occurs when the pain signals remain in the active state inside the nervous system for a span of weeks and months after the healing of the injury. The physical impact of this pain is utmost restriction in the mobility, build-up of tension in the muscles, lack of energy and loss of appetite. One of the major conditions for the persistence of chronic pain is the prevalence of the illness called Fibromyalgia. In this condition, the presence of pain stimulating impulses called substance P is three times higher than in normal circumstances. This leads to the aggravation of pain for longer periods. This phenomenon is sometimes also called the wind-up phenomenon where the unrelenting pain becomes bad to worse. In this situation, the nerve fibers get hyper-active in sending the painful impulses to the body.

Fatigue is another reason for the occurrence of chronic pain in the body. This condition can range from mild levels to incapacitating levels. In worse, scenarios, it becomes so severe that people find troubles in keeping up with the demands of their job. Fatigue is one of the major reasons for the growing tension between the muscles which lead to what we know as chronic pains.